To fully embrace and benefit from digital transformation, individuals, firms and governments need to be confident that engaging in the digital environment to conduct their social and economic activities will bring more benefits than downsides. Such downsides can arise from various sources of uncertainties affecting digital technologies, data and cross-border flows. Many are related to potential digital security incidents, information asymmetries, power imbalances or jurisdictional challenges exacerbated by the digital environment. These may translate into breaches of laws and regulations such as privacy, consumer protection or product safety, intended to reduce these imbalances and challenges. To ensure trust, it is critical to mitigate as much as possible such uncertainties.